Idiopathic Granulomatous Mastitis: A Comprehensive Review

Main Article Content

Namrata Mahansaria

Abstract

Idiopathic granulomatous mastitis (IGM) is a rare chronic inflammatory breast disease. IGM poses diagnostic and therapeutic challenges due to its complex clinical presentation and poorly understood etiology. Although auto immunity has been blamed for its etiology, it has not been fully elucidated. Its histopathology is characterized by non-caseating granulomas. IGM usually presents as tender mass in the breast, mimicking inflammatory malignancy. This review aims to summarise current knowledge on the epidemiology, pathogenesis, clinical features, diagnostic approach, and management strategies of IGM.

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How to Cite
Idiopathic Granulomatous Mastitis: A Comprehensive Review. (2024). Jharkhand Surgical Chronicles, 1(1). https://jhsurgicalchronicles.com/index.php/en/article/view/22
Section
Review Article

How to Cite

Idiopathic Granulomatous Mastitis: A Comprehensive Review. (2024). Jharkhand Surgical Chronicles, 1(1). https://jhsurgicalchronicles.com/index.php/en/article/view/22

References

Kessler E, Wolloch Y. Granulomatous mastitis: a lesion clinically simulating carcinoma. Am J Clin Pathol 1972;58:642-6.

Freeman CM, Xia BT, Wilson GC, et al. Idiopathic granulomatous mastitis: a diagnostic and therapeutic challenge. Am J Surg 2017;214:701-6.

DeHertogh DA, Rossof AH, Harris AA, et al. Prednisone management of granulomatous mastitis. N Engl J Med. 1980;303:799-800. doi:10.1056/NEJM19801002303140

Lai EC, Chan WC, Ma TK, et al. The role of conservative treatment in idiopathic granulomatous mastitis. Breast J. 2005;11:454–6. doi:10.1111/j.1075-122X.2005.00127.

Raj N, Macmillan RD, Ellis IO, et al. Rheumatologists and breasts: immunosuppressive therapy for granulomatous mastitis. Rheumatology (Oxford). 2004;43:1055-6. doi:10.1093/rheumatology/keh256

Altintoprak F, Kivilcim T, Ozkan OV. Aetiology of idiopathic granulomatous mastitis. World J Clin Cases. 2014;2:852-8. doi:10.12998/wjcc.v2.i12.852

Barreto DS, Sedgwick EL, Nagi CS, et al. Granulomatous mastitis: etiology, imaging, pathology, treatment, and clinical findings. Breast Cancer Res Treat. 2018;171:527-34. doi:10.1007/s10549-018-4870-3

Mahmodlou R, Dadkhah N, Abbasi F, et al. Idiopathic granulomatous mastitis: dilemmas in diagnosis and treatment. Electron Physician. 2017;9:5375–9. doi:10.19082/5375

Aghajanzadeh M, Hassanzadeh R, Alizadeh Sefat S, et al. Granulomatous mastitis: Presentations, diagnosis, treatment and outcome in 206 patients from the north of Iran. Breast. 2015;24:456–60. doi:10.1016/j.breast.2015.04.003

Pluguez-Turull CW, Nanyes JE, Quintero CJ, et al. Idiopathic Granulomatous Mastitis: Manifestations at Multimodality Imaging and Pitfalls. Radiographics. 2018;38:330–56. doi:10.1148/rg.2018170095

Ertürk TF, Çakır Ö, Yaprak Bayrak B, et al. Local steroid treatment: an effective procedure for idiopathic granulomatous mastitis, including complicated cases. J Invest Surg. 2022;35:745-51. doi:10.1080/08941939.2021.1943589

Ren Y, Zhang J, Zhang J, et al. Combining intralesional steroid injection with oral steroids in patients with idiopathic granulomatous mastitis. Medicine (Baltimore). 2023;102

Cabioglu N, Uras C, Mutlu H, et al. Local steroid injection in severe idiopathic granulomatous mastitis as a new first-line treatment modality with promising therapeutic efficacy. Front Med (Lausanne). 2023;10:1251851. doi:10.3389/fmed.2023.1251851